11Excessive Fatigue or Persistent Unease
Excessive tiredness, depression and general unease are not specific to colorectal cancer. But it is a sign that something is wrong with the body.
This could be due to internal blood loss, an indication of colon cancer. Your immune system may be using up more energy than usual to fight the disease. The cancerous cells could be depleting you of energy. Also, the overload of toxins caused by being unable to pass waste efficiently might be behind the lethargy.